产品货号：
Z33108
中文名称：
Alpha Tubulin/TUBA1A抗体
英文名称：
Anti-Alpha Tubulin/TUBA1A Antibody (Clone#7B12)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Alpha Tubulin/TUBA1A Antibody (Clone#7B12) |
| 指标别名 | alpha tubulin;TUBA1A;TUBA3 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | TUBA1A |
| 克隆号 | 7B12 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | E.coli-derived human Tubulin alpha recombinant protein (Position:N18-A403). |
| 实际分子量 | 55KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Tubulin is the major constituent of microtubules.It binds two moles of GTP,one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins.The genes encoding these microtubule constituents belong to the tubulin superfamily,which is composed of six distinct families.Genes from the alpha,beta and gamma tubulin families are found in all eukaryotes.The alpha and beta tubulins represent the major components of microtubules,while gamma tubulin plays a critical role in the nucleation of microtubule assembly.There are multiple alpha and beta tubulin genes,which are highly conserved among species.This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes.Northern blot studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly,intellectual disability,and early-onset epilepsy caused by defective neuronal migration.Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Uniprot ID | Q71U36 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | tubulin alpha 1a/tubulin alpha 1b/tubulin alpha 1c |
| 蛋白名全称 | Tubulin alpha-1A chain/Tubulin alpha-1B chain/Tubulin alpha-1C chain |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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